Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Pecam1  platelet/endothelial cell adhesion molecule 1   (Synonyms: Cd31, PECAM-1)
Results	Reference
1	J:123910 Aase K, Ernkvist M, Ebarasi L, Jakobsson L, Majumdar A, Yi C, Birot O, Ming Y, Kvanta A, Edholm D, Aspenstrom P, Kissil J, Claesson-Welsh L, Shimono A, Holmgren L, Angiomotin regulates endothelial cell migration during embryonic angiogenesis. Genes Dev. 2007 Aug 15;21(16):2055-68
1	J:153050 Bogani D, Siggers P, Brixey R, Warr N, Beddow S, Edwards J, Williams D, Wilhelm D, Koopman P, Flavell RA, Chi H, Ostrer H, Wells S, Cheeseman M, Greenfield A, Loss of mitogen-activated protein kinase kinase kinase 4 (MAP3K4) reveals a requirement for MAPK signalling in mouse sex determination. PLoS Biol. 2009 Sep;7(9):e1000196
1	J:334017 Bunce C, Barske L, Zhang G, Capel B, Biased precursor ingression underlies the center-to-pole pattern of male sex determination in mouse. Development. 2023 Mar 1;150(5):dev201060
1	J:244575 Chen J, Luo Y, Hui H, Cai T, Huang H, Yang F, Feng J, Zhang J, Yan X, CD146 coordinates brain endothelial cell-pericyte communication for blood-brain barrier development. Proc Natl Acad Sci U S A. 2017 Sep 05;114(36):E7622-E7631
1	J:217601 Delgado-Olguin P, Dang LT, He D, Thomas S, Chi L, Sukonnik T, Khyzha N, Dobenecker MW, Fish JE, Bruneau BG, Ezh2-mediated repression of a transcriptional pathway upstream of Mmp9 maintains integrity of the developing vasculature. Development. 2014 Dec;141(23):4610-7
1	J:335574 Dong X, Zhang Q, Yu X, Wang D, Ma J, Ma J, Shi SH, Metabolic lactate production coordinates vasculature development and progenitor behavior in the developing mouse neocortex. Nat Neurosci. 2022 Jul;25(7):865-875
1	J:137630 Dubois NC, Adolphe C, Ehninger A, Wang RA, Robertson EJ, Trumpp A, Placental rescue reveals a sole requirement for c-Myc in embryonic erythroblast survival and hematopoietic stem cell function. Development. 2008 Jul;135(14):2455-65
1	J:104223 Fagman H, Andersson L, Nilsson M, The developing mouse thyroid: embryonic vessel contacts and parenchymal growth pattern during specification, budding, migration, and lobulation. Dev Dyn. 2006 Feb;235(2):444-55
1	J:345606 Gonzalez Galofre ZN, Kilpatrick AM, Marques M, Sa da Bandeira D, Ventura T, Gomez Salazar M, Bouilleau L, Marc Y, Barbosa AB, Rossi F, Beltran M, van de Werken HJG, van IJcken WFJ, Henderson NC, Forbes SJ, Crisan M, Runx1+ vascular smooth muscle cells are essential for hematopoietic stem and progenitor cell development in vivo. Nat Commun. 2024 Feb 23;15(1):1653
1	J:173280 Goossens S, Janzen V, Bartunkova S, Yokomizo T, Drogat B, Crisan M, Haigh K, Seuntjens E, Umans L, Riedt T, Bogaert P, Haenebalcke L, Berx G, Dzierzak E, Huylebroeck D, Haigh JJ, The EMT regulator Zeb2/Sip1 is essential for murine embryonic hematopoietic stem/progenitor cell differentiation and mobilization. Blood. 2011 May 26;117(21):5620-30
1	J:170840 Guadix JA, Ruiz-Villalba A, Lettice L, Velecela V, Munoz-Chapuli R, Hastie ND, Perez-Pomares JM, Martinez-Estrada OM, Wt1 controls retinoic acid signalling in embryonic epicardium through transcriptional activation of Raldh2. Development. 2011 Mar;138(6):1093-7
1	J:194396 Hagerling R, Pollmann C, Andreas M, Schmidt C, Nurmi H, Adams RH, Alitalo K, Andresen V, Schulte-Merker S, Kiefer F, A novel multistep mechanism for initial lymphangiogenesis in mouse embryos based on ultramicroscopy. EMBO J. 2013 Feb 12;32(5):629-44
1	J:272613 Koutelou E, Wang L, Schibler AC, Chao HP, Kuang X, Lin K, Lu Y, Shen J, Jeter CR, Salinger A, Wilson M, Chen YC, Atanassov BS, Tang DG, Dent SYR, USP22 controls multiple signaling pathways that are essential for vasculature formation in the mouse placenta. Development. 2019 Feb 22;146(4):dev174037
1	J:137720 Kubota Y, Hirashima M, Kishi K, Stewart CL, Suda T, Leukemia inhibitory factor regulates microvessel density by modulating oxygen-dependent VEGF expression in mice. J Clin Invest. 2008 Jul;118(7):2393-403
1	J:126240 Lu X, Le Noble F, Yuan L, Jiang Q, De Lafarge B, Sugiyama D, Breant C, Claes F, De Smet F, Thomas JL, Autiero M, Carmeliet P, Tessier-Lavigne M, Eichmann A, The netrin receptor UNC5B mediates guidance events controlling morphogenesis of the vascular system. Nature. 2004 Nov 11;432(7014):179-86
1*	J:240101 Lv J, Wang L, Gao Y, Ding YQ, Liu F, 5-hydroxytryptamine synthesized in the aorta-gonad-mesonephros regulates hematopoietic stem and progenitor cell survival. J Exp Med. 2017 Feb;214(2):529-545
1*	J:316445 Marks-Bluth J, Khanna A, Chandrakanthan V, Thoms J, Bee T, Eich C, Kang YC, Knezevic K, Qiao Q, Fitch S, Oxburgh L, Ottersbach K, Dzierzak E, de Bruijn MF, Pimanda JE, SMAD1 and SMAD5 Expression Is Coordinately Regulated by FLI1 and GATA2 during Endothelial Development. Mol Cell Biol. 2015 Jun;35(12):2165-72
1	J:275137 Munro DAD, Wineberg Y, Tarnick J, Vink CS, Li Z, Pridans C, Dzierzak E, Kalisky T, Hohenstein P, Davies JA, Macrophages restrict the nephrogenic field and promote endothelial connections during kidney development. Elife. 2019 Feb 13;8:e43271
1*	J:221192 Prasitsak T, Nandar M, Okuhara S, Ichinose S, Ota MS, Iseki S, Foxc1 is required for early stage telencephalic vascular development. Dev Dyn. 2015 May;244(5):703-11
1	J:137647 Robert-Moreno A, Guiu J, Ruiz-Herguido C, Lopez ME, Ingles-Esteve J, Riera L, Tipping A, Enver T, Dzierzak E, Gridley T, Espinosa L, Bigas A, Impaired embryonic haematopoiesis yet normal arterial development in the absence of the Notch ligand Jagged1. EMBO J. 2008 Jul 9;27(13):1886-95
1	J:137277 Ross A, Munger S, Capel B, Bmp7 regulates germ cell proliferation in mouse fetal gonads. Sex Dev. 2007;1(2):127-37
1	J:327069 Sa da Bandeira D, Kilpatrick AM, Marques M, Gomez-Salazar M, Ventura T, Gonzalez ZN, Stefancova D, Rossi F, Vermeren M, Vink CS, Beltran M, Henderson NC, Jung B, van der Linden R, van de Werken HJG, van Ijcken WFJ, Betsholtz C, Forbes SJ, Cuervo H, Crisan M, PDGFRbeta(+) cells play a dual role as hematopoietic precursors and niche cells during mouse ontogeny. Cell Rep. 2022 Jul 19;40(3):111114
1	J:314577 Shao X, Liu K, Fan Y, Ding Z, Chen M, Zhu M, Weinstein LS, Li H, Li H, Galphas Relays Sphingosine-1-Phosphate Receptor 1 Signaling to Stabilize Vascular Endothelial-Cadherin at Endothelial Junctions to Control Mouse Embryonic Vascular Integrity. J Genet Genomics. 2015 Nov 20;42(11):613-624
1*	J:219365 Simmons O, Snider P, Wang J, Schwartz RJ, Chen Y, Conway SJ, Persistent Noggin arrests cardiomyocyte morphogenesis and results in early in utero lethality. Dev Dyn. 2015 Mar;244(3):457-67
1	J:63242 Spyropoulos DD, Pharr PN, Lavenburg KR, Jackers P, Papas TS, Ogawa M, Watson DK, Hemorrhage, impaired hematopoiesis, and lethality in mouse embryos carrying a targeted disruption of the Fli1 transcription factor. Mol Cell Biol. 2000 Aug;20(15):5643-52
1	J:63424 Takakura N, Watanabe T, Suenobu S, Yamada Y, Noda T, Ito Y, Satake M, Suda T, A role for hematopoietic stem cells in promoting angiogenesis. Cell. 2000 Jul 21;102(2):199-209
1	J:213584 Vincent SD, Mayeuf-Louchart A, Watanabe Y, Brzezinski JA 4th, Miyagawa-Tomita S, Kelly RG, Buckingham M, Prdm1 functions in the mesoderm of the second heart field, where it interacts genetically with Tbx1, during outflow tract morphogenesis in the mouse embryo. Hum Mol Genet. 2014 Oct 1;23(19):5087-101
1*	J:80219 Voss AK, Gruss P, Thomas T, The guanine nucleotide exchange factor C3G is necessary for the formation of focal adhesions and vascular maturation. Development. 2003 Jan;130(2):355-67
1*	J:103443 Wilhelm D, Martinson F, Bradford S, Wilson MJ, Combes AN, Beverdam A, Bowles J, Mizusaki H, Koopman P, Sertoli cell differentiation is induced both cell-autonomously and through prostaglandin signaling during mammalian sex determination. Dev Biol. 2005 Nov 1;287(1):111-24
1	J:191306 Yang Y, Garcia-Verdugo JM, Soriano-Navarro M, Srinivasan RS, Scallan JP, Singh MK, Epstein JA, Oliver G, Lymphatic endothelial progenitors bud from the cardinal vein and intersomitic vessels in mammalian embryos. Blood. 2012 Sep 13;120(11):2340-8
1*	J:238623 Zhou W, He Q, Zhang C, He X, Cui Z, Liu F, Li W, BLOS2 negatively regulates Notch signaling during neural and hematopoietic stem and progenitor cell development. Elife. 2016 Oct 10;5:e18108